General side effects are mostly present during the first 1-4 weeks while the body adapts to the drug. Almost all SSRIs are known to cause either one or more of these symptoms. A person receiving paroxetine treatment may experience a few, all, or none of the following side-effects, and most side-effects will disappear or lessen with continued treatment, though some may last throughout the duration.
Teratogenicity: Pregnant women are advised not to take the drug due to possible fetal heart defects.
Changes in weight and appetite
Changes in sexual behaviour
Increased feelings of depression and anxiety (initially)
Aggressive behavior (esp. in children)
Possible suicidal behavior
Possible congenital malformations
Restlessness or Akathisia
Uncharacteristic levels of aggression
Individuals experiencing any of the following symptoms should contact their doctor immediately:
Jaw, neck, and back muscle spasms
Fever, chills, sore throat, or flu-like symptoms
Yellowing of the skin or eyes
Black, tarry stools (this can indicate upper GI bleeding)
Paroxetine and other SSRIs have been shown to cause sexual side effects in most patients, both males and females. Although usually reversible, these sexual side effects can sometimes last for months, years or possibly indefinitely even after the drug has been completely withdrawn. This disorder is known as Post SSRI Sexual Dysfunction.
Author of The evidence, however, is clear, the Seroxat scandal
Citizens Commission on Human Rights Award Recipient (Twice)
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