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Monday, February 19, 2007

Paroxetine (SEROXAT) From Wikipedia, the free encyclopedia

Side effects

General side effects are mostly present during the first 1-4 weeks while the body adapts to the drug. Almost all SSRIs are known to cause either one or more of these symptoms. A person receiving paroxetine treatment may experience a few, all, or none of the following side-effects, and most side-effects will disappear or lessen with continued treatment, though some may last throughout the duration.


Pupil dilation


Teratogenicity: Pregnant women are advised not to take the drug due to possible fetal heart defects.[11]



Changes in weight and appetite

Changes in sexual behaviour

Increased feelings of depression and anxiety (initially)

Dry mouth

Aggressive behavior (esp. in children)

Possible suicidal behavior

Possible congenital malformations


Restlessness or Akathisia

Sodium depletion



Muscle weakness

Muscle ache

Uncharacteristic levels of aggression

Serotonin syndrome

Individuals experiencing any of the following symptoms should contact their doctor immediately:

Jaw, neck, and back muscle spasms

Fever, chills, sore throat, or flu-like symptoms

Yellowing of the skin or eyes

Black, tarry stools (this can indicate upper GI bleeding)

Paroxetine and other SSRIs have been shown to cause sexual side effects in most patients, both males and females[12]. Although usually reversible, these sexual side effects can sometimes last for months, years or possibly indefinitely even after the drug has been completely withdrawn. This disorder is known as Post SSRI Sexual Dysfunction.