1)How common is the withdrawal syndrome?
2)In what proportion of patients is it severe?
3)What regime should be used for withdrawing the drug?
4)How is the syndrome best treated, other than re- starting paroxetine, e.g. should an alternative SSRI be used?
5)Are there particular patient characteristics which predispose them to the syndrome?
Failing satisfactory answers to these questions will inevitably lead to the substitution of alternative therapies. - Ian K. Campbell, partner Heacham Group Practice
These are people who were prescribed Paroxetine (or one of the other SSRI/SNRI drugs), without any warning of the addictive nature, or severe side effects upon withdrawal that all too often accompany these drugs.
I can only hope that similar action will be taken against all drugs that are within the SSRI/SNRI classification of drugs. The population so adversely affected by these drugs may appear to be nominal when written up as a percentage in the drug labeling insert, but in reality- with so many now being prescribed these new "wonder" drugs for everything from mild depression to PMS, there are millions now using these drugs, most without proper follow up care. The "small percentage" factor now translates into thousands, possibly hundreds of thousands who are so adversely affected.
I know from personal experience. I have never taken any of these drugs, but we lost our fourteen year old son to suicide, which I firmly believe was brought on by his own adverse reaction to Prozac, and I have watched my husband suffer terribly in attempting to withdraw from Paxil. I would venture to guess that those who are adversely affected by these drugs are much higher than even the 7-10% that is now being proposed.
I encourage you to investigate further into the hundreds of thousands of other "anecdotal" evidences from those using the other SSRI/SNRI drugs. If you don't take the responsibility to do this now, the reality will manifest itself, as has been the case with Paroxetine. There are simply too many people now who are beginning to realize that they were denied the opportunity of "Informed Clinical Consent". These people are not laboratory rats who should be subjected to such experimentation. Listen to what they have to say!
Oh, and one more thing, until there is absolute proof positive that one has a "serotonin imbalance", it would be best if this theory ceased to be pushed upon the public as fact. Until there is a method in place to determine what is a "normal" serotonin level in a patient, and a method to determine how much that level should be tampered with to achieve the desired results, the pharmaceutical firms should cease comparing patients diagnosed with depression, anxiety, bi-polar disorder or any other number of "mental health disorders" to those diagnosed with diabetes. You can measure the level of insulin needed to obtain the correct balance needed for someone with diabetes. Not so with serotonin. - Dawn Rider, Administrative KOTM Early Intervention
I was put on Paxil after my daughter was born to treat Post Partum Depression. After about 9-10 months my doctor and I determined that I could start coming off. She suggested step down to 15mg from 20mg the first week taking 15mg every day for 7 days then 10mg everyday for 7days, then 5mg for 7days then none. This just didn't work. I remember getting very agitated, irritable, feeling very out of control, and weepy. Every time I stepped into a hot shower I would feel very flushed and dizzy. This dizziness would dissipate, but to this day this still happens. I stepped down from 20mg - 15 mg ok, spent probably about 2 weeks at 15mg until I felt comfortable enough to step down again to 10mg. Stayed at 10mg for about 3-4 weeks, and 5mg for about another 3-4 weeks. A process that, by my doctor's and the drug company's estimation, should have only taken 4 weeks took me about 8-10 weeks.
During my time on Paxil if I missed a dose the symptoms I described above, would roar in and wouldn't subside until about 3-4 hours after I took the missed dose.
I also believe that my daughter's seizures as an infant were caused by Paxil withdrawal. I started on Paxil before I gave up trying to breast feed (having had breast reduction surgery 3 years earlier, severely limited my milk production to almost none). Her seizures started within several of days of stopping breast feeding. Timing coincidence. I don't think so.
This drug can be very helpful, but needs to be used very carefully. - Julia A Mandeville, Software QA Engineer
If discontinuation reactions’ occur in patients stopping [Paxil], the majority will experience symptoms that are mild to moderate in intensity, and are usually limited to two weeks
I think patients have nothing to fear from taking Seroxat.
Read the new book, The Evidence, However, Is Clear...The Seroxat Scandal
By Bob Fiddaman
AVAILABLE FOR DOWNLOAD HERE
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