Monsanto Roundup Lawsuit

Sunday, August 09, 2009

Kauffman Study – Selective Serotonin Reuptake Inhibitor (SSRI) Drugs: More Risks Than Benefits?

An interesting paper has just been released and was sent to me by Janice Simmons of the Seroxat User Group. The paper, by Joel Kauffman, is calling for a review regarding the benefits v risks of SSRi's and non SSRi's [such as Effexor]

He writes:

"At most 30% of patients receive a benefit from SSRIs beyond the large placebo effect in certain mental conditions, especially depression, according to a recent meta analysis of published trials. An equally recent meta-analysis of all SSRI trials submitted to the FDA showed a small benefit for the severely depressed patients only. Many early unpublished trials did not show any benefit. Adverse effects are common, occurring in up to 75% of subjects."

This table from Kauffman's paper shows the SSRi's and non-SSRi's that are problematic.



Kauffman also writes:

"From 35 healthy volunteer studies on paroxetine, pre-launch, the results of only 14 appeared. From 35 pre-launch healthy volunteer studies on sertraline, only seven appeared. Among the unpublished trials, there was one in which all volunteers dropped out because of agitation (akathisia). In published work on sertraline, data excluded material on behavioral toxicity, including at least one suicide of a Adverse Effects of healthy volunteer, and in a different trial, 2 of 20 volunteers became intensely suicidal. This last is consistent with the dropout rate of 5% for agitation alone in actual trials. It is also consistent with Lilly’s animal studies, in which previously friendly cats treated with fluoxetine started growling and hissing—an unheeded warning."

I'm sending a copy of the paper to the MHRA. They need to know [I think they do already]

Meantime, a copy can be downloaded here.

If the author of the paper wishes for me to remove the download then I will. I think it is too important to be paid for but will respect his wishes if he wants it removed.

Fid

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'THE EVIDENCE, HOWEVER, IS CLEAR...THE SEROXAT SCANDAL' By Bob Fiddaman
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