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Wednesday, April 27, 2011

Sniff Sniff - Nasal Spray to Beat Depression






Those wacky scientists are at it again. Not content with selective serotonin reuptake inhibitors to increase the levels of serotonin in the human brain in pill shape form, they now, it appears, are on the verge of releasing a nasal spray that can help beat depression!

According to the Daily Mail:

"The spray, based on a natural brain chemical, could be effective within two hours, compared to several days for some of the most widely used antidepressant drugs.

"The liquid is released at the top of the nose and is designed to penetrate the brain areas involved in mood".

The Daily Mail cites that the trial is being carried out at the Mount Sinai School of Medicine in New York, where researchers are investigating the use of the spray containing neuropeptide Y.

A quick browse of the Mount Sinai School of Medicine clinical trials page shows the following:

Intranasal Administration of Neuropeptide Y in Healthy Men

ID Number 05-0986
Principal Investigator(s)
Adriana Feder

Department(s) or Division(s)
Psychiatry

Description
The purpose of this study is to help understand how Neuropeptide Y, a natural substance found in the brain that can regulate stress and anxiety, can be effectively delivered to the human body. Male volunteers who have no history of psychiatric illness, are in excellent physical health, and have no history of nasal or spinal disorders or surgery may be eligible to participate.


Contact Information
Gang Wu
(212) 241-9336
gang.wu@mssm.edu

Recruiting Patients: Yes

The new trial, which involves 15 volunteers aged 25 to 45, is designed to investigate how well the spray and neuropeptide Y work in the brain, and the effects will be compared with a placebo.

I'm left wondering if the placebo will be inserted through the nasal passage as well?

This isn't the first time nasal sprays have been touted as 'alternatives' to pills. In fact, the Daily Mail has reported on many nasal sprays in the past.

The nasal spray that could help fight Alzheimer's

British scientists develop nasal spray that could stop the flu virus from laying you low

New nasal spray could protect from deadly meningitis and pneumonia

Nasal spray can stop miscarriage

The sweet smell of success: Scientists invent memory-boosting nasal spray

Nasal spray to help impotence

Nasal spray hailed as latest HRT treatment

The articles continue including a love hormone spray that could help shy people at parties, a 'cuddle' spray that could ease symptoms of autism, a spray that reduces brittle bone risk and a spray that protects you from bird flu.

So folks, if the 'depression' spray gets the go-ahead you will no longer have to wait for the pills to 'kick-in'. Within two hours your depression will apparently be beaten into submission with the aid of a nozzle and a liquid formulation that gets straight to the root of the problem - quite where that root is, is still, as yet, unknown.

So, not only do you have antidepressant addiction to look forward to, you also have nasal spray addiction to look forward to as well! [See Rhinitis Medicamentosa]

I wonder if these wacky scientists have thought about suppositories to cure depression? I can just see the advertising slogan. "Do you sit at parties, do you wish you could be more active and dance the night away? Ask your doctor for 'Arseache' and rest assured that you will sit no longer at parties.

"Arseache comes in different sizes. Tapering with a special arse nozzle is recommended should you choose to wean off Arseache."


Funny...but I seriously wouldn't put it past them!

Fid


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