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Sunday, January 18, 2009

SSRI chemical imbalance theory

The following is an extract taken from a featured article called 'The Media and the Chemical Imbalance Theory of Depression' by Jonathan Leo & Jeffrey R. Lacasse.

Abstract

The cause of mental disorders such as depression remains unknown. However, the idea that neurotransmitter imbalances cause depression is vigorously promoted by pharmaceutical companies and the psychiatric profession at large. We examine media reports referring to this chemical imbalance theory and ask reporters for evidence supporting their claims. We then report and critique the scientific papers and other confirming evidence offered in response to our questions. Responses were received from multiple sources, including practicing psychiatrists, clients, and a major pharmaceutical company. The evidence offered was not compelling, and several of the cited sources flatly stated that the proposed theory of serotonin imbalance was known to be incorrect. The media can play a positive role in mental health reporting by ensuring that the information reported is congruent with the peer-reviewed scientific literature.

Before you read the full article, take a look at the following:

Lexapro - Manufacturer - H. Lundbeck A/S - Denmark – (Forest Laboratories in the US) - "Lexapro corrects this chemical imbalance andmay help relieve the symptoms of depression" [Patient Information Leaflet]

Cipramil / Marketed under the Brand Name Celexa in the US - Manufacturer - H. Lundbeck / American partner Forest Laboratories: Google search "Celexa helps to restore the brain’s chemical balance by increasing the supply of a chemical messenger in the brain called serotonin."

Pristiq - Manufacturers - Wyeth: "As an SNRI, PRISTIQ affects the levels of two neurotransmitters thought to play a key role in depression — serotonin and norepinephrine. Serotonin and norepinephrine are chemicals that occur naturally in the brain. While no one knows for sure what causes depression, many experts believe that it may occur when neurotransmitters are out of balance." Pristiq website

Aropax [Seroxat] - Manufacturer - GlaxoSmithKline: "Aropax corrects the chemical imbalance and so helps relieve the symptoms of depression." GSK Australia

Geodon - Manufacturer - Pfizer: "How GEODON Works. Doctors believe GEODON helps balance certain natural chemicals in your brain. Balancing these chemicals helps treat your symptoms of acute manic or mixed episodes associated with bipolar disorder. And that can help you feel better." - Geodon Website

There are many more. Now read the article


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