Recent paroxetine Literature

Reading through this recent paper [Paroxetine-induced increase in LDL
cholesterol levels] it appears that paroxetine [Seroxat] can significantly increases your LDL [bad] cholesterol level.

“A similar 9% paroxetine-induced increase in LDL-C observed in the large number of psychiatric patients suffering from comorbid established CHD would be detrimental from a cardiovascular perspective and would oppose the new NCEP therapeutic goals of decreasing LDL-C levels by 30–40% in high and moderately high-risk patients.”

Venlafaxine [Effexor] is also mentioned in the paper:

"A double-blind, randomized, placebo-controlled efficacy study comparing the efficacy of short-term administration of paroxetine, venlafaxine and placebo in patients with social anxiety disorder (SAD) found that paroxetine and venlafaxine, a serotonin and norepinephrine reuptake inhibitor, induced a statistically significant rise in total cholesterol, but the increase in LDL-C did not reach statistical significance (Liebowitz, et al., 2005)."

Two antidepressant drugs - both with a high number of adverse reaction reports.

Both remain on the market.

The paper can be downloaded here.

Fid

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'THE EVIDENCE, HOWEVER, IS CLEAR...THE SEROXAT SCANDAL' By Bob Fiddaman
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