Zantac Lawsuit


Researching drug company and regulatory malfeasance for over 16 years
Humanist, humorist

Tuesday, August 25, 2009

Recent paroxetine Literature

Reading through this recent paper [Paroxetine-induced increase in LDL
cholesterol levels] it appears that paroxetine [Seroxat] can significantly increases your LDL [bad] cholesterol level.

“A similar 9% paroxetine-induced increase in LDL-C observed in the large number of psychiatric patients suffering from comorbid established CHD would be detrimental from a cardiovascular perspective and would oppose the new NCEP therapeutic goals of decreasing LDL-C levels by 30–40% in high and moderately high-risk patients.”

Venlafaxine [Effexor] is also mentioned in the paper:

"A double-blind, randomized, placebo-controlled efficacy study comparing the efficacy of short-term administration of paroxetine, venlafaxine and placebo in patients with social anxiety disorder (SAD) found that paroxetine and venlafaxine, a serotonin and norepinephrine reuptake inhibitor, induced a statistically significant rise in total cholesterol, but the increase in LDL-C did not reach statistical significance (Liebowitz, et al., 2005)."

Two antidepressant drugs - both with a high number of adverse reaction reports.

Both remain on the market.

The paper can be downloaded here.

Fid

ORDER THE PAPERBACK
'THE EVIDENCE, HOWEVER, IS CLEAR...THE SEROXAT SCANDAL' By Bob Fiddaman
SIGNED COPIES HERE OR UNSIGNED FROM CHIPMUNKA PUBLISHING

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