Zantac Lawsuit


Researching drug company and regulatory malfeasance for over 16 years
Humanist, humorist

Tuesday, November 10, 2009

Why Antidepressants Don't Work


Image: chemistryland.com



An interesting article was sent to me earlier today from Steph Gatchell. For those that don't know, Steph is the mother of Sharise Gatchell. Sharise commited suicide whilst on the SSRi, Seroxat and Steph has long since been campaigning about the dangers of these types of drugs.

The article in question here was written by Dr. Mercola who writes on mercola.com. He writes:

"The site takes up virtually all of my time and I had to stop seeing patients in 2005 so I can pursue my passion of educating the public about health truths so hundreds of thousands of people don't have to die prematurely every year because of multinational corporations that put profits ahead of serving their customers."

Dr. Mercola's latest article, 'Why Antidepressants Don't Work', is well worth a read, as are the comments underneath.

Fid

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Reflections of an Obsession - Part II - Unredacted


'Sher', approx 2 months before her untimely death.


The story of Sheryl Tilbrook, as written by her father, Stuart Jones.

I originally ran with this back in March 2009. At that time, the author, Stuart Jones, wished for names and places to be redacted.

He has since reconsidered.

Reflections on an Obsession.


10/6/04 (Taken from notes on the 6/6/04)

On the morning of the sixtieth anniversary of D Day I had a respite from my obsessional research into the events which surrounded my daughter Sheryls death: As for a brief while I thought of the enormity of that assault on Hitler's Atlantic Wall defences
.
I wondered at the sheer enormity of the task. At the stark horror and at the courage and determination of those who fought that day. Of those who died. And of what we owe to them and to that battles successful outcome.

I thought of the events which had led to that momentous day. Of the blundering foreign policy and diplomacy of self-interest-orientated nation states, which led to the rise to power of Hitler's Germany, with all that evil regimes monstrous consequences.

The reason that D Day was able to, and did succeed despite the high cost, was that the price of failure would have been immeasurably higher.

I remembered relating these facts to Sheryl. It was the year of her O level examinations, she was given “Hitler's Germany” for her history subject matter, and I recalled the way she quite shamelessly bullied, teased and cajoled me into all but actually writing the text for her examination essay, and it came as no surprise when We received an A grade. I remember the poignant regret in me, as I watched some of the child in her change as she learned how the Nazis came to power and she learned of the atrocities of Hitler’s Third Reich. And I recall the pride I felt, as I saw her develop a personal resolution that such a terrible thing should never happen again.

Sheryl learned of the process of natural justice, from the decision of the Allies to try war criminals, and the resultant Nuremberg Code. And the formation of the United Nations Charter and told me that she was going to be a barrister.

Her further A level studies including law, grammar, history and literature, took her beyond my limited knowledge, yet she still included her family in her further education and I remember her humorous observations on Cider with Rosie reducing her family to helpless tears.

At that point I broke down. Tears induced by other emotions than merriment streamed down my face.

They were the tears of grief. Gradually, although my sense of loss was a tangible knot of choking pain, the grief changed to a sense of outraged indignation and I realised that I had drawn a parallel between my reminiscences and my families current plight.

The War in Europe was the result of a nations schizophrenic support for a madman. The research into Sheryl’s Death, which I have been engaged in for over three years, was instigated by the corporate schizophrenia of a pharmaceutical company and my thoughts returned to the time of my daughters death and of how it came about.

The full story can be downloaded HERE

Previous:

Reflections of an Obsession - Part I - The Eulogy

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Monday, November 09, 2009

Reflections On An Obsession... Part I - The Eulogy


Sheryl: 2 months prior to her death.



Reflections On An Obsession... Part I - The Eulogy

Sheryl Tilbrook was a quite extraordinary person, a human being who stood out amongst other people.... Until she went to her trusted medical advisor and got a prescription for an ssri...and died.

Over the coming weeks, months, however long it takes, I shall be highlighting the case of Sheryl Tilbrook, beloved daughter of Stuart and Claudette Jones, sister of Nadine, Richard, Kathryn, Nicola, Stuart & John, aunty of Katie, Martin, Gethin, Nathan, Adam, Aaron, Luke, Kelly, Cristyn, Cariad-Sher & Sophie.

I have previously covered the story of Sheryl [1], though at the time, Stuart, her father, wished for names to be redacted. He, along with his wife, Claudette, now feels the time is right to go public with this.

On 18th May 2001 Sheryl went to her GP because she was having a down day and was lacking in energy. Her GP prescribed Sheryl the SSRi antidepressant, 28 x Cipramil tablets and 7 x Zopliclone.

On the 20th May she was admitted to the intensive care unit.

On the 24th May when all hope had gone, her mother and brother turned her life support machine off.

On the 2nd June, 2001, Sheryl's parents and four generations of family members and friends gathered together to say goodbye to her. She had a guard of honour from 8 members of the London Fire Brigade in full dress uniform.

Sheryl had taken an overdose of the Selective Serotonin Re-Uptake Inhibitor [SSRi] Cipramil.

I would like to highlight the eulogy written by Claudette, Sheryl's mother, I feel this is important as it brings home the stark reality of it all.

No parent should have to bury their child, particularly when that child put their trust in the medical profession and the pharmaceutical industry.

Stuart and Claudette Jones want justice to prevail. They want their questions answered.

I hope the platform I am about to give them eases their pain and creates an awareness that brings about answers.

Fid

[1] Reflections on an Obsession

Eulogy by Claudette Jones

SHER,

Wife, Daughter,Sister, Aunty and Friend, if I only said this it would be a lot but Sher was and is much more than this to everybody who knew her, she was a confidant and champion to all those she loved and cared for.

From a very young age she showed what she was made of, if you had Sher on your side you knew she'd make short work of any problem, because she was fiercely loyal and loved with great passion.

Her nieces and nephews knew when aunty Shershi said she would do something then come what may, it would be done.

They loved each other dearly and liked nothing more than to spend time together especially if this meant a sleep over, 'cause that would mean being thoroughly spoilt, she never begrudged anything and was always there when they needed her.

To her brothers and sisters she was more than their baby sister she was their best friend and had with each and every one of them a very special bond that could never be broken by anything including her death. Their love for each other and that bond will stay forever no matter what.

As a daughter we couldn't have hoped for better, she was bright, lively, intelligent with a tremendous sense of fun, even when she was so ill 10 years ago and on the life support machine she never lost her humour.

Her favourite nurse Margaret got renamed 'rat bag'. On one occasion Sheryl even absconded (wheel chair,oxygen tank, everything went) and Sher with the aid of her brothers just nipped down to the 'Deer's' Leap for a lunchtime drink and a whacky fag, unfortunately her 'Rat Bag' Aunty Margaret just happened to be passing and caught them all out. I think it was the first and last time that a patient from the ITU had not only gone walk-about but gotten away with it as well.

As a wife there was no better, loving, loyal, supportive.. she had no equal. She was so proud of Ron when he became a full time fireman and it's fair to say that part of Sheryl was in the fire service with him.

I've tried to give you all a sence of Sheryl and what made her tick, I hope I've achieved that but I would say to you all don't feel sorry for us, we are the lucky ones, we're proud to have known, loved and cared for our Sher for the years we were able, yes we'll grieve and won't ever stop missing her, but we'll carry her in our hearts forever and know that when we need her she'll be there and one day we'll be together again.

Baby you are the best.


----

Fid

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Friday, November 06, 2009

LEST WE FORGET



Add a poppy to your blog for this weekend.

Remember all those who have gone before us today.

Also let us not forget the brave who are currently fighting out in Afghanistan.

The Armed Forces have my utmost respect.

Brothers in arms.

Total and utter respect for those both living and whom have fallen.

We shall live forever in your debt.

Cut and paste and share this message with your friends

Thanks

Fid




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SWINE FLU VACCINE, PANDEMRIX, UNSAFE IN THOSE WITH ENVIRONMENTAL ILLNESSES


Image: patentdocs.typepad.com


Source: The Environmental Illness Resource


The following statement (kindly translated by CSN) from the German Professional Association of Environmental Medicine outlines their position specifically on the Pandemrix® H1N1 vaccine providing a scientific rationale for each point on a substantial list of concerns.


Press release of the German Professional Association of Environmental Medicine (Deutscher Berufsverband der Umweltmediziner – DBU).


From 26. October 2009.


Swine flu [H1N1] vaccine is unsuitable for patients with chronic multi-system illnesses. Pandemrix® poses substantial health risk with respect to mass immunization programs due to the lack of proof of safety. Because of the producer’s release from liability by the German Federal Government (BRD), the risk of adverse reactions and/or permanent damage due to the vaccine rests with the patient.

The German Professional Association of Environmental Medicine (DBU) has, in spite of press releases from the BRD, the Paul-Ehrlich-Institute, as well as the vaccine producer’s assurances of safety, serious concerns relating to Pandemrix® (GlaxoSmithKline), the only vaccine which has been approved for mass vaccination by the BRD.

The DBU discusses at this point neither the medical use of immunization in general nor the necessity of such measures in the, up until now, mild course of the swine flu pandemic.


Our criticism is directed only against the pandemic vaccine Pandemrix®.

There exists considerable doubt as to the effectiveness of the vaccine: during the licensing phase, the vaccine tested had a 40% higher portion of virus antigen (5. 25µg) than the vaccine (3.75µg) now being delivered. An unequivocal consensus has not been reached as to whether the vaccination should be given once or twice a season.

There exists considerable doubt concerning the safety of the adjuvanted active amplifier since it is being used for the first time. The vaccine contains 27.4mg AS03, an emulsion of polysorbate, squalene and tocopherol. Sufficient studies are lacking, because in the test phase, only the development of antibody titers was determined as a surrogate criterion, and not any potential adverse reactions.

The producer as well as government agencies have concealed the fact that squalene, if used subcutaneously or intramuscularly is an inflammatory immune activation immunogen, unlike when ingested. (Squalene is, among other things, for example, naturally contained in olive oil.)

Autoimmune diseases can be provoked by squalene; already existing ones can be activated. Squalene has been connected with the emergence of Guillan-Barré Syndrome (GBS) and is now considered a trigger for Gulf War Syndrome (GWS). In animal studies squalene brought on rheumatoid arthritis.

Squalene from food sources is mainly incorporated into membranes in the body. The production of squaline antibodies resulting from an immunization sets off chronic inflammation of the membranes, which explains diseases such as Gulf War Syndrome and also degenerative neurological diseases such as Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Chronic Inflammatory Demyelinating Polyneuropathy and Guillan-Barré Syndrome.

The delivery of vaccine in multiple dose ampules is obsolete. In single dose ampules the mercury used for preservation, as in thimerosal – which is included in Pandemrix – would be unnecessary. Also, mercury has been proven to set off autoimmune diseases.

Since the vaccine has not been tested on either young children or pregnant women (Ethics Commission objection), the call to give preference in the first phase of vaccination to precisely this particularly endangered segment of the population represents an improper and totally unjustifiable field test.

The vaccine poses a higher risk than the swine flu itself for patients with environmental illness and for patients with compromised immune systems (e.g. AIDS).

The vaccine producer GlaxoSmithKline (GSK), according to the contract with the BRD, is largely exempt from liability. In case of damage from the vaccination, the affected vaccinee would have to sue the government and therefore the country of Germany, usually a futile exercise.

To avoid the trap of liability, the doctor giving the vaccination must meticulously inform the patient of all risks concerning the vaccination and the vaccine. It is recommended to give this information in the presence of an assistant and to have it be confirmed by the patient’s signature. The explanation should also include the liability features. Also the indication that other, lower risk vaccines are available in Europe and that due to a faulty decision by the German government, they are currently not available to the German population. This information should definitely be included in the explanation.


Read More HERE

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Wednesday, November 04, 2009

**Exclusive - MHRA Launch Pilot Scheme to Push for More ADR's to be Reported.


Image: wikimedia.com


As a long time critic of the MHRA's Yellow Card reporting system, credit where credit is due, I have to applaud their latest pilot scheme. I think it shows that the MHRA are aware that the Yellow Card system needs work and, it would appear, that they are actually doing something about it.

Back in October, they launched the scheme with the launch of video advertisements in doctors surgeries, and promotional activity to GPs and other primary care professionals at Primary Care Live (a big conference/exhibition in London).

Simon Gregor, MHRA Communications Director, told me, "The campaign is not in one specific area in the UK, but we are working with particular groups of surgeries. For the leaflets, we are working with those surgeries which use something called the IDS leaflet system, which is a means of getting the YC leaflets into the surgeries. There are 6000 surgeries which use this system, and we are aiming to distribute leaflets through all of them."

He added, "For the video, we are using a service called the Life Channel, which has a presence in 400 GP surgeries."

Some of the key points of this scheme are thus:

 The MHRA has a responsibility and is committed to continually promoting the use of the YCS as a means of gathering information on side effects to medicines.

 The YCS was officially extended to members of the public in February 2008, following a successful pilot.

 Data from reporting volumes demonstrate a clear link between periods of campaigning raising awareness and numbers of reports received.

 MHRA have embarked upon a campaign to further raise awareness amongst members of the public and health professionals.

 For the public campaign MHRA are producing leaflets for pharmacy and general practice, a 30 second video explaining the scheme to patients will be shown on the Life Channel and use of the public media is planned. We are also linking the Yellow Card Scheme website to more external sites such as NHS Choices.

 For the health professional campaign MHRA will be increasing its presence at professional meetings by having exhibition stands to promote the Scheme. The priority area will be conferences attended by primary care workers such as Primary care live and Royal College of GPs annual meeting.

 In both campaigns key message will be to report side effects online.

 Results will be measured by increased reporting from the target groups and increased proportion of online reports.

Here is the ad.




It will be interesting to see how this pans out, Simon Gregor has promised to relay any results to me once the scheme runs its course and we shall be meeting again in the early part of next year to discuss the findings of the scheme.

I will, as always, keep you all posted.

Fid

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SSRi's and Alcohol


Image: freedigitalphotos.net



"We suggest that antidepressant product warnings regarding alcohol, hitherto non-specific and unhelpful, will need to be reconsidered."


An interesting pdf file was sent to me from a fellow advocate last night. I only have the summary but it throws light on the subject of consuming alcohol whilst on SSRi's.

The findings:

from
Abstracts of the 9th World Congress of Biological Psychiatry, Paris, June 2009

P-10-004
Violence as a side - effect of antidepressants: Provocation by alcohol
David Menkes
University of Auckland, Waikato Clinical School, Hamilton, New Zealand
Andrew Herxheimer

Objectives: Based on case-reports and epidemiological data, we reported the rare induction of serious violence by antidepressant treatment (PLoS Med 3(9): e372). Given alcohol’s prevalence and tendency to disinhibit behaviour, we studied its association with SSRI-induced violence.

Methods: We analyzed some 200 cases drawn from our medicolegal practices, web-based patient discussion lists, and ADR reports to government authorities in Canada and the USA. Assessment was based on standard criteria for drug-effect causality (CIOMS), taking into account apparent sources of bias.

Results: A distinct syndrome of uncharacteristic disinhibition with alcohol was detected in 40 individuals of either sex during treatment with SSRIs or venlafaxine. Outcomes included 12 homicides (2 of which were double), suicide, serious assault, unintended sexual intercourse, and other damaging or markedly embarrassing social behaviour. In the majority of cases, memory for the episode was lacking, often completely so. For most individuals, modest or usual amounts of alcohol were involved, with evidence that these had been well tolerated before antidepressant treatment,and after its discontinuation (challenge-dechallenge). In several cases, re-exposure to the same or related antidepressant reproduced the phenomenon (rechallenge).

Conclusions: We identify a distinct and forensically important interaction between alcohol and SSRI antidepressants. Aggregated pharmacovigilance data (in preparation) corroborate the existence of this phenomenon. We suggest that antidepressant product warnings regarding alcohol, hitherto non-specific and unhelpful, will need to be reconsidered.

Fid

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Tuesday, November 03, 2009

UK Regualtor and Pfizer: From the silver screen to the small screen.

Earlier this year [Jan 2009] I wrote about the launch of an advertising campaign in cinemas across Britain that featured an advertisement regarding the safety of buying drugs online. The advert showed a man opening a package which contained a packet of pills, he opens the pills, swallows one then seconds later is seen pulling a dead rat from his mouth... this to symbolize how dangerous it is buying drugs online.

Today, the MHRA have announced that the ad is coming to the smaller screen [Television] and the 30 second or so ad will be screened after 11pm because it is 'considered so shocking'.

The ad was made from the money of Pfizer, no coincidence that Pfizer's biggest competitors are those online websites that sell Viagra... or am I just being cynical?

One only has to type the word 'Viagra' into Google to see the competition Pfizer face. [HERE]

Genius marketing spin would have us believe that Pfizer are genuinely concerned for the public taking fake pills. Is the real concern here driven by profits falling?

It's nice to see the regulator talking with advocates but working alongside pharmaceutical companies kind of leaves a bitter taste in my mouth.

Here is the ad that ran in cinemas up and down the country earlier this year.




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Today in Parliament


Pic: parliamentlive.tv

Source: Parliament TV


Introduction



The Lord Bishop of Lichfield will be introduced.


*The Earl of Sandwich


to ask Her Majesty’s Government how they will ensure that doctors and pharmaceutical companies fully recognise the long-term side effects of prescribed tranquillisers and anti-depressants, and the nature of withdrawal symptoms.


Watch it from 2.30 pm [GMT] on Parliament TV HERE


Hat - Tip: Ruth

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Monday, November 02, 2009

Survey Shows Consumers Take Pot Luck When Buying Herbal Medicines


Image: responsesource.com


A survey conducted by consumer website www.herbfacts.co.uk reveals that 64 percent of the participants believe all herbal medicines to be as safe as OTC medicines. But 82 percent do not know how to identify which ones have been independently assessed and approved for sale by UK governing body, the Medicines and Health Products Regulatory Agency (MHRA).

Source HERE

I think that anyone who puts a herb or prescription pill in their mouth [even over the counter pills] are pretty much taking pot luck - vaccines too!

Fid

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Switzerland restricts use of GlaxoSmithKline swine flu vaccine


Image: justgetthere.us


Some recent swine flu articles that reached me over the weekend.

Switzerland restricts use of GlaxoSmithKline swine flu vaccine.

Psyorg reports:

Switzerland restricted the use of British drugs group GlaxoSmithKline's swine flu vaccine Pandemrix, excluding pregnant women, minors and people over the age of 60.

They add:

The regulatory authority Swissmedic said it had received data on the vaccine for adults, but not for pregnant women and very little data for children.
"For this reason, Swissmedic has not yet authorised the administration of Pandemrix to pregnant women, children under the age of 18 and adults over 60," the regulator said in a statement.

More HERE



Evie Pringle's 5th instalment 'Profit Driven Swine Flu Propaganda - Pump Up the Volume' is now available and focuses largely on mercury and the H1N1 vaccines.

She writes:

Most American are unaware that flu vaccines still contain thimerosal and that to avoid mercury, they have to ask for mercury-free shots. On November 13, 2007, the Milwaukee Journal Sentinel ran the headline: "Most flu shots contain mercury, but few know it."

More HERE



Finally, Medpage Today is running a survey that poses the question:

Does Vaccine Fear Put Kids at Risk?

In some school districts, half of parents are unwilling to have their children vaccinated against the H1N1 pandemic flu, despite the fact that children are among the hardest hit by this flu.

As of 10am GMT, 2ND November 2009, the results are pretty much neck and neck.

The survey asks...

Is a reluctance to vaccinate children?

Here are the results thus far:




CLICK ON IMAGE TO ENLARGE


Fid

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Sunday, November 01, 2009

UK ADDICTION

An article that has appeared in the Independent newspaper has been sent to me. Thanks to Truthman, Ruth, Cyndi.

It is a report on Britain's epidemic of pill addiction. The Independent writes:

"The Department of Health has launched a review of the million-plus patients addicted to prescribed drugs in the UK in a tacit admission that attempts to control the problem over the last two decades have failed."

The article adds;

On Tuesday, Lord Montagu, the Earl of Sandwich, is to seek details of the Government review in the House of Lords and will say how the problem of addiction has impacted his own family.

He said: “Since January a member of my family has been suffering from acute withdrawal from this prescribed drug [a benzodiazepine]: his dreadful symptoms mean he is confined to his room, unable to work and attend to his family. He receives no government or medical support because there is none.”

A familiar story to those of us that are or ever have been hooked on antidepressants. Remember, SSRi's are not addictive, at least according to the manufacturers and medicines regulator. Benzo's are addictive, for some time now many advocates have been saying the same about SSRi's. Will it take a a member of the Knighthood to highlight the dangers of SSRi's because one of his family members has been affected by them?

The BNF is a guidebook for doctors, it is updated every six months. The current information for benzo's is pretty thorough whilst the information for guidance on SSRi withdrawal is poor, in fact it is very poor.

I cannot go into too much detail but there are movements behind the scenes, the wheels have already been set in motion to edit the poor guidance in the BNF.

Are SSRi's addictive?

The difficulty here lies in those individuals who make claims that 'they had no trouble withdrawing' - I don't dispute that they did but it appears that the MHRA treat these sort of anecdotal reports with a gold star whilst reports of patients suffering withdrawal are currently logged and... well, that's pretty much it.

Last week, Janice Simmons of the Seroxat User Group and I met with the Communications Director of the MHRA, Simon Gregor. I have previously wrote about that meeting here.

We covered the 'addiction' problem quite extensively. Where the MHRA are failing [and they know it] is the system set up to report adverse drug reactions [Yellow Card]

The system, I believe, is not robust enough to collect and correlate data. There is NO mandatory law that states a doctor MUST report an adverse event of a drug. Patients remain largely unaware that such a reporting system exists and many doctors surgeries only carry the odd few yellow cards [normally in the back cover of the BNF]

Credit has to be given to the MHRA for realising that their system is flawed, it has taken them long enough but things are about to change. Simon told both Janice and I that a pilot scheme is soon to be set up in the UK that will try to encourage more reporting of adverse drug reactions from patients. I liked the idea and, I believe, it will improve the current system.

The MHRA are aware that the need to do more to encourage people to report adverse drug reactions is paramount [by both patients and doctors] and this 'pilot scheme' is a step in the right direction. We also spoke about the importance of a wide range of healthcare professionals being "in the loop" both on Yellow Card reporting and on new information/warnings about drugs eg pharmacists, coroners.

The pilot scheme will be launched soon and will involve a promotional push for reporting ADR's.

The failure of the Yellow Card system has been highlighted by many. Charles Medawar was banging the drum about the 'flawed system' many years ago when transparency at the MHRA didn't exist. Myself and Janice and other advocates have also heavily criticised the system over the years.

If enough people bang the drum, the MHRA will not be able to cover their ears from the noise.

I will criticise the MHRA on here and in person if they appear to be failing in certain areas and I will also applaud them if I feel they are doing right. With the pilot scheme they should take a bow. I just hope that it is not a PR exercise to stifle its critics. I genuinely believe it is not.

Fid

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