Zantac Lawsuit


Researching drug company and regulatory malfeasance for over 16 years
Humanist, humorist
Showing posts with label Lilly. Show all posts
Showing posts with label Lilly. Show all posts

Monday, March 07, 2022

GUEST POST: P-450 Test and Multiple Chemical Sensitivity

 


I've heard many stories over the years regarding the troubles people have experienced whilst taking brain pellets marketed as 'antidepressants.' Kerri's guest post (below) is yet another example of how patients are pushed from pillar to post, often having to find their own way to resolve matters relating to brain pellet adverse events because of a severe lack of knowledge from prescribing physicians.

The three pellets featured in Kerri's story were, at a point in time, blockbuster products raking in billions of dollars for the drug companies who marketed and manufactured them, namely Lilly (Prozac) and GlaxoSmithKline (Paxil) and Pfizer (Zoloft). Three apparent drugs that are supposed to help but, as is my experience, cause more problems than the original 'illness' they are prescribed for. They all, allegedly, work in pretty much the same way. Drug company reps will tell you that A is better than B and C because, well, because that's what they are paid to do. They have no scientific evidence that one is more tolerable and causes less side-effects than the other.

I find it difficult to believe that neither Lilly, GlaxoSmithKline or Pfizer  knew nothing about the problems caused by the three products mentioned below, moreover, the journeys many millions face when taking them.

This is just a small part of Kerri's journey. She writes to warn others and to create an awareness that all is not lost if you, or someone you know, suffers the same fate as she.

Bob Fiddaman

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I was taught to trust the doctors. I was taught to trust the prescriptions.  I was taught to trust the assessments I received from hospitals. And I did…but, this trust of these medical recommendations nearly killed me.

My name is Kerri Lynn and I was born in Long Beach CA, but was raised in the upper Midwest. I grew up in a dysfunctional home and early on, I gravitated towards addictive tendencies.  I strived to make good choices at this time, however, my best efforts to live life on life’s terms were mostly self-destructive.

"I was restless, irritable and discounted all the time being newly sober and I needed help facing life, or so I thought." 

At 13, I discovered drinking.  I partied all the time until my addiction stopped working for me.  I chased other self-destructive behaviors and relationships.  My out-of-control nature led to an ultimatum from loved ones: I had to find a solution how not to be self-destructive.

Pain and circumstances drove me to seek help from 12-Step Recovery.  This was really a challenge and about 60 days into this sober journey, I sought help from my family doctor.  I was restless, irritable and discounted all the time being newly sober and I needed help facing life, or so I thought.  My first prescription was for 20 mg of Prozac. 3 Days into this first prescription, I was unable to walk or talk.  I was severely anxious and my brain was racing and telling me to do delusional things like run outside naked.  I experienced Homicidal and Suicidal Ideation (I have come to understand that these are the symptoms of Serotonin Syndrome/Akathisia). I was panicking due to my reaction to this prescription, though I had no awareness that it was the prescription that was causing these symptoms.  I had to reach out to a former counselor to sorts things out.

I met with my former counselor the following Monday. I finally revealed I was taking Prozac, and he immediately called my prescribing physician to get me off this prescription.  This was the beginning of a 13-year nightmare with prescribed medications.

40mg of Paxil was my next prescription.  A year into taking this antidepressant, I woke up one morning and could not emotionally feel anything. I was terrified.  I called my doctor again and he tried yet another substitute of Zoloft.  At that point, all hell broke loose.  My doctor tried Paxil one more time and this sent me to the hospital.  Between 2000 and 2006, I was Hospitalized on 3 separate occasions due to drug toxicity or cold turkey drug withdrawal. 

"I exhausted every potential care and specialty option locally."

During these nightmare days, I was entertained with my expanded medical vocabulary.  I learned words like suicidal ideation, disassociation, delusion, hallucination, profuse night-sweats, rapid irregular heartbeats and agoraphobia.  We must not forget the bladder loss or rectal haemorrhaging, nor the black outs that would last more than 24 hours, when they would randomly introduce new medications.  And my favorite suffering were the overwhelming panic attacks.

Sadly, my entire investment in the “healing process” to this point only led to my condition becoming more and more dire.  The medical assessments only were dealing with a random set of symptoms that were mostly caused by the prescription and I could not break the cycle, no matter what I did or took.  Almost every diagnosis made things worse and added to my growing list of “untreatable symptoms.”  I exhausted every potential care and specialty option locally.  I even spent 2 weeks at the world renown Mayo Clinic only to achieve an inaccurate diagnosis once again of Visceral Extreme Hypersensitivity.  When I return to my home, I felt defeated and my local hospital would no longer allow me to make appointments, unless first reviewed by management over the phone.  These doctors thought I was crazy.

It is always darkest before the dawn.  I was under the care of many physicians.  Many were a significant part of the problem and few were graciously a part of what would be my life-changing solution.   I was blessed to be introduced to the Cytochrome P-450 test which analyses DNA and genetic strengths and deficiencies.  From this accurate genetic assessment, it was discovered that I have both fast and slow processes in my liver and kidneys.  This finally expressed a causality between reception and rejection of various medications.  It was also determined accurately that I am missing the GSTM-1/ Glutathione Gene.   It was finally determined that my true ailment was Multiple Chemical Sensitivity and all previous diagnoses actually placed me in grave risk by triggering my symptoms. The synthetic nature of the drugs being prescribed to me were actually poisoning me and triggered my multiple chemical sensitivity.  During the course of 13 years of prescriptions, my body has been damaged so that I will most likely be significantly chemically sensitive for the remainder of my days. 

"It is my hope that my story can guide people to new strategies so that nobody ever has to suffer like I did."

My hope is that by sharing my story that we can come to a new responsibility about how we seek and receive diagnoses.  The medical profession has a mission statement of seeking to do no harm.  This is not always the case.  From my experience, a measured suspicion is the best approach.  I now take the responsibility of doing my own medical research.  I trust my instincts and I am my own advocate.  Through my difficult journey my local provider actually became the first hospital in the country to study the P-450 genetic test.  I strongly recommend this assessment be the starting point.  Don’t utilize the P-450 as a last resort.

I am now 11-years medication free and stable.  I have to live the rest of my life being critically aware of my environment and surroundings due to my chemical sensitivity. However, today I have a strategy for living that works. It is my hope that my story can guide people to new strategies so that nobody ever has to suffer like I did.

~ Kerri Lynn

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You can listen to Kerri's story in her own words here via the brilliant Akathisia Stories, a co-production of MISSD and Studio C.

You can read more about Cytochrome P450 (CYP450) tests here

Footnote:

Test limitations

Although they have potential, CYP450 tests have limitations:

Tests are available for only certain medications. Also, each test is specific to only one medication, so a change in medication may require another test.

Testing can't predict which medication will work best for you — it can only provide clues.

Not all insurance companies cover the costs of these tests.


Thursday, November 16, 2017

Business as Usual Means Bad News for Consumers


As an advocate for drug safety, I sometimes feel as if I'm pissing in the wind. Today is one of those times. (For American readers, the Cambridge Dictionary describes pissing in the wind as "trying to do something when there is no hope of succeeding.")

This week President Trump nominated Alex Azar as the next Secretary of the Department of Health and Human Services (HHS). Azar is former senior vice president of corporate affairs and communication for US pharmaceutical giant Eli Lilly. This US announcement comes on the heels of similar incestuous behavior by the UK government which recently announced Andrew Witty, former head of GlaxoSmithKline, has been selected to head its new pathway, 'Accelerated Access Review' (AAR). Days later, GSK's website highlighted another kick in the teeth for British drug consumers: Patrick Vallance, who is currently GSK's president of research and development, will become the UK government's new Chief Scientific Adviser.

What a sick few weeks for health consumers. Three top executives from Big Pharma land positions that are supposed to better protect health consumers by ensuring scientific information is accurate, and drugs are safe and effective. These three appointments should prompt Britain and US residents to take notice and be on full DEFCON alert. I'm certain families across the globe who have lost loved ones to Prozac and Paxil won't be jumping for joy at this week's announcements, and I imagine their dead relatives are turning in their graves.

Lilly & GSK are two companies that have frequently been sued by consumers who were harmed by their dangerous products. Further, both companies have engaged in abhorrent and illegal tactics to peddle their pills. Some of these unscrupulous behaviors include paying doctors to prescribe, bribing government officials, and fraudulently marketing drugs for unapproved uses. But apparently, this type of leadership is rewarded by governments that prefer corporate collusion to consumer care.

GSK and Lilly have paid billions in fines and lawsuits because their illegal activities caused the suffering and deaths of countless innocent men, women, and children. In 2009, Lilly was fined $1.42 billion to resolve a government investigation regarding off-label promotion of the antipsychotic Zyprexa. Zyprexa had been approved for the treatment of certain psychotic disorders, but Lilly admitted to promoting the drug in elderly populations to treat dementia. The government also alleged that Lilly targeted primary care physicians to promote Zyprexa for unapproved uses and “trained its sales force to disregard the law."

Similarly, in 2012, GSK agreed to pay a fine of $3 billion to resolve civil and criminal liabilities regarding its promotion of drugs and its failure to report safety data. This is the largest healthcare fraud settlement in the United States to date. The company pled guilty to misbranding the drug Paxil for treating depression in patients under 18, even though the drug was not approved for children. GSK also pled guilty to failing to disclose safety information to the FDA about the diabetes drug Avandia. These pharmaceutical companies don't mind paying a couple of billion dollars here and there for criminal violations because shady criminal behavior reaps more sales profits than does subsequent fines. This unethical behavior is just part of pharma's business plan.

Back to Those Incestuous Appointments

Alex Azar has had previous connections to the US government. He was deputy secretary of Health and Human Services under George W. Bush and served as the chief operating officer for two years. In that role, Azar oversaw such agencies as the Food and Drug Administration (FDA), the National Institutes of Health, the Centers for Disease Control and Prevention, and the Centers for Medicare and Medicaid Services. In May 2007, Azar became senior vice president of corporate affairs and communication for Lilly. This revolving door employment agency is standard US practice. Corporate execs leave the industry for cushy jobs in government, then they leave government for industry and lobbying jobs, etc.

This incestuous fox guarding the hen house is commonplace and will continue to put consumers at great risk. It was US President George W. Bush who named Eli Lilly President and CEO, Sidney Taurel, as a Homeland Security Advisory Council member in 2002. Further, soon after the Homeland Security Act was signed in 2002, New York Times columnist Bob Herbert discovered what had been slipped into the Act at the last minute. On November 25, 2002, he wrote, “Buried in this massive bill, snuck into it in the dark of night by persons unknown…was a provision that incredibly will protect Eli Lilly and a few other big pharmaceutical outfits from lawsuits by parents who believe their children were harmed by thimerosal.” (Thimerosal is a mercury-based preservative that is used in vaccines. It was developed by Lilly in the 1920s and by the 1990s its use was widespread)

In 2003, Bush appointed Taurel to the President’s Export Council. The same year, “60 Minutes II” aired a segment on Lillygate and Prozac. Lilly's patent for Prozac had run out so they began marketing a new drug, Prozac Weekly. According to 60 Minutes II, Lilly sales reps gained access to “confidential” patient information records and mailed out free samples of Prozac Weekly. Regulations, proposed under Bill Clinton and later implemented under George Bush, contained a provision that allowed healthcare providers the right to sell a person’s confidential medical information to marketing firms and drug companies.

Bush was later rewarded for his job placements and overseeing provisions when he left the White House. He went straight to Eli Lilly headquarters where he served as an Eli Lilly Board of Director.

You scratch my back, I'll scratch yours, huh?

Assuming he's confirmed, Azar will oversee 11 agencies including the FDA, Center for Disease Control (CDC), National Institutes of Health (NIH), Administration for Children and Families (ACF) and Centers for Medicare & Medicaid Services (CMS).

When Patrick Vallance of GSK takes over the role of UK Government Chief Scientific Adviser, he will oversee science and technology-related activities and recommend policies to the Prime Minister and  Cabinet. He will also sit as chair of the UK’s Scientific Advisory Group for Emergencies.

Witty's new title is self-explanatory. He will head a new UK government initiative known as 'Accelerated Access Review' (AAR) where his role is to get new drugs and devices on the market quickly.

If you want to know more about how Lilly operates, I highly recommend John Cornwell's book, "The Power to Harm: Mind, Medicine, and Murder on Trial." It's a jaw-dropping insight regarding how far Lilly went to cover up the deadly ADRs caused by their lucrative drug, Prozac. If you want to know how GSK operate, well, there are more than 2,000 posts about GSK's shenanigans on my blog alone.

Unreported Terror & Risk

These appointments are scary and put citizens at greater risk of being harmed by unsafe, ineffective drugs, many of which should never have been approved. In both the UK and the US, we see frequent media reports about terrorist threats and acts, but we almost never hear news about pharma created deaths. When was the last time you heard a news report or read an article highlighting that prescription drugs are the fourth leading cause of death? In America, I chalk this up to the lucrative drug advertisements that essentially pay for TV news production. In the UK we don't have drug ads, but we still have pharma money negatively influencing government policy and political appointments.

Hiring CEO's of criminal corporations to protect citizens is wrong. But these types of crimes pay. If you don't like the status quo, you can petition your respective government and share your disgust. I'm sure they'll be happy to send you a form letter response within 30 days...

So, back to pissing in the wind: It's understandable I'm disgusted by this week's news. It's easy to throw up my hands when hearing such outrageous appointments. But sometimes those who've lost a loved one to pharma help me persevere. As one mom whose child died from pharma products recently said, "To the world, my child was just one person, but to me, she was the world. If my advocacy saves even one child, I have saved someone else's world."


In other news involving incestuous revolving doors, the FDA has now approved a new "digital pill." The pill contains a sensor that digitally tracks whether or not patients have ingested their medication. And what pill has this sensor been embedded into? ~ aripiprazole, (Abilify) a drug used to treat multiple mental mood disorders, including bipolar disorder and schizophrenia.

On top of this, the commissioner of the FDA, Scott Gottlieb, is opposing a natural plant, Kratom, (mitragyna speciosa) that could help people effectively treat an addiction caused by opioids.

More on the aripiprazole and kratom scandals next week.

Bob Fiddaman












Friday, June 29, 2012

CafePharma Boards



Was browsing through the boards over at CafePharma earlier, I enjoy reading some of the threads on the GlaxoSmithKline page where disgruntled employees, many of them reps, attack the likes of Andrew... [**coughs]...sorry, Sir Andrew Witty.

I'm sure many of the anonymous posters on these boards are legit and are genuinely miffed about the company they work for. Long hours, promises of bonuses, changes in company mantra, promoting drugs off-label to doctors whilst wining and dining them or bringing their staff in coffee from Starbucks or donuts from the company that tell you to 'dunk them'

With what seems like a bitchin' pot of messages to Glaxo it surprises me that none of the disgruntled army of ex and current employees have ever thought about blowing the whistle on those they target.

Sure, it's great to beeatch and off-load your angst against the company but does it really change anything?

Glaxo aren't the only pharmaceutical company that comes under fire, there's different boards for each of the leading pharmaceutical companies, each of which are ladened with current and ex-employees attacking the various policies and management [ahem mismanagement] of the companies they once worked/work for.

I'm writing this in the hope that someone from these boards will pick up on it. By all means carry on bitchin', it makes great reading, but do something about it. Let's face it, the companies you work/ed for don't exactly look after you as they do their key opinion leaders [thought leaders] do they?

When was the last time a rep was given a big, fat meaty cheque for promoting a drug? Okay, they get a wage and, sometimes a bonus [when it's paid on time] but nowhere near to the sums paid to thought leaders such as Karen Wagner, Josef Biederman and/or Marty "bling bling" Keller.

I'd be miffed if I were an employee or ex-employee of major pharmaceutical companies. I'd be pissed at the fact that my employee had used me to promote drugs to children when, in actual fact, my company knew all along that these drugs were not safe for children. I'd be pissed that my company had paid out millions of dollars to thought leaders yet made me work extra-long hours for a mere pittance and a performance based bonus... based on how I could promote drugs for populations that weren't meant for those populations.

I'd be so pissed off with allowing myself to be manipulated by company spin just so I couldn't see the wood through the trees, the dense forest hiding the facts that I had been used as a drug peddler, my objective being to push doctors to prescribe to the vulnerable populations out there... Children.

Hey ho, thankfully I've never been down that road. My conscience is clear.

The bitchin' on CafePharma continues, the main objective, it seems, being just a place to let off steam.

Only way these disgruntled masses can get back at those who treated them with contempt is to start blowing whistles. I'm sure there are many whom have witnessed fraudulent acts against the US government. Whether or not they have been part of these acts is irrelevant - they can and should try to bring about change.

I'm a big fan of US attorneys, Baum Hedlund. They've kicked GlaxoSmithKline's ass to infinity... and beyond on many occasions. They, I'm sure, would welcome employees or ex-employees of big pharma to bitch at them down the phone.

Whistleblower suits are becoming more popular these days, particularly against pharmaceutical companies.

Allen Jones blew the whistle on Johnson & Johnson’s Janssen unit for promoting the off-label use of Risperdal in children. J&J settled with a payment of $158 million, some of which went Jones' way for blowing the whistle. The settlement came less than a month after J&J officials agreed to pay more than $1 billion to the U.S. and a number of states to end a civil investigation into Risperdal marketing practices.

Cheryl Eckard, who humiliated GlaxoSmithKline with regard to the appalling lapses at their manufacturing plant in Cidra, Puerto Rico, was also paid handsomely for whistleblowing. A cool $96 million went her way.

Helen Ge was a former contractor at Takeda Pharmaceutical Co. Ltd. She learned that Takeda have been playing down risks of three of their drugs, particularly when combined with other drugs. She was fired from her position when she brought this to the attention of her seniors. She has now filed a whistleblower suit.

The more the merrier, I say.

So, I do hope that this post makes it across cyberspace to CafePharma. I also hope that I can somehow tap into the conscience of those who throw the flames anonymously on the boards over there.

Do what's right. Blow the whistle.

Just click on the image to start the ball rolling.



Alternatively, drop me an email... cos I just love blowing the whistle.


Email me



Fid

ORDER THE PAPERBACK 'THE EVIDENCE, HOWEVER, IS CLEAR...THE SEROXAT SCANDAL' By Bob Fiddaman US and CANADA HERE OR UK HERE

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Wednesday, April 08, 2009

Is British TV Promoting Erectile Dysfunction Tablets?

I sat in horror last night as an advert appeared on TV regarding erectile dysfunction problems. To my knowledge this is the first of its kind to be aired on British TV although I may be wrong?

Here is the 30 second ad




American/Canadian readers of this blog will probably think, 'What's the big deal, we get ads like this all the time'. Here in the UK we don't. In fact I thought it was illegal to advertise any prescription drug.


I found the ad misleading, "40% of men over 40 may have suffered some degree of erectile dysfunction," says the voiceover. This claim is then juxtaposed with a pop-up subtitle that states: "12 year study of US males. The Massachusetts Male Aging Study 1994."


Firstly, why is an ad airing on British TV using data that refers to American men and secondly, why are they using a study to back up their claim that is 15 years old?


The ad promotes the website 40over40.com, a website sponsored by Eli Lilly and Company.

I pondered complaining to the MHRA but it seems they have already received a complaint about this particular ad, a complaint that they did not uphold!



Hardly surprising as earlier this year the MHRA teamed up with Pfizer to air an ad in British cinemas that, I believe, was nothing more than a PR campaign for Pfizer's Viagra. See here and here.



This end, I have made a complaint to the Advertising Standards Authroity [ASA]



Fid





** Prohibition of advertisements for medicinal products on prescription only
7. Subject to regulation 11, no person shall issue an advertisement which is likely to lead to the use of a relevant medicinal product which is a medicinal product for supply by prescription only and which is subject to any of the restrictions imposed by section 58(2) of the Act.

Source: The Medicines (Advertising) Regulations 1994



Read the new book, The Evidence, However, Is Clear...The Seroxat Scandal

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Please contact me if you would like a guest post considered for publication on my blog.